| QB | DT | ||
| Matthew Stafford | Ndamukong Suh | ||
| Shaun Hill | Corey Williams | ||
| Kellen Moore (UD) | Nick Fairley | ||
| R.J. Archer (TO) | Sammie Lee Hill | ||
| Andre Fluellen | |||
| RB | Michael Cosgrove (UD) | ||
| Jahvid Best | |||
| Mikel Leshoure | DE | ||
| Kevin Smith | Cliff Avril | ||
| Joique Bell | Kyle Vanden Bosch | ||
| Keiland William | Lawrence Jackson | ||
| Stefan Logan | Willie Young | ||
| Stephfon Green (UD) | Everette Brown | ||
| Ronnell Lewis (RO) | |||
| FB | Ugo Chinasa (PS) | ||
| James Bryant | Edmon McClam (UD) | ||
| WR | LB | ||
| Calvin Johnson | Stephen Tulloch | ||
| Nate Burleson | Justin Durant | ||
| Titus Young | DeAndre Levy | ||
| Ryan Broyles (RO) | Doug Hogue | ||
| Maurice Stovall | Ashlee Palmer | ||
| Jarett Dillard | Tahir Whitehead (RO) | ||
| Lance Long | Travis Lewis (RO) | ||
| Dominique Curry | Slade Norris (PS) | ||
| Nate Hughes (PS) | Carmen Messina (UD) | ||
| Terrence Toliver (PS) | Ronnie Sneed (UD) | ||
| Patrick Edwards (UD) | |||
| Wallace Miles (TO) | CB | ||
| Chris Houston | |||
| TE | Jacob Lacey | ||
| Brandon Pettigrew | Alphonso Smith | ||
| Tony Scheffler | Drew Coleman | ||
| Will Heller | Dwight Bentley (RO) | ||
| Nathan Overbay (PS) | Chris Greenwood (RO) | ||
| Alex Gottlieb (UD) | Jonte Green (RO) | ||
| Austin Wells (UD) | Justin Miller | ||
| Dontrell Johnson (UD) | |||
| OT | |||
| Jeff Backus | S | ||
| Gosder Cherilus | Louis Delmas | ||
| Riley Reiff (RO) | Amari Spievey | ||
| Corey Hilliard | Erik Coleman | ||
| Jonathan Scott | John Wendling | ||
| Jason Fox | Sean Jones | ||
| Don Carey | |||
| OG | Ricardo Silva (PS) | ||
| Rob Sims | |||
| Stephen Peterman | K | ||
| Jacques McClendon (PS) | Jason Hanson | ||
| Joshep “J.C.” Oram (UD) | Derek Dimke (UD) | ||
| Rodney Austin (UD) | |||
| P | |||
| OC | Ryan Donahue | ||
| Dominic Raiola | Ben Graham | ||
| Dylan Gandy | |||
| Dan Gerberry (PS) | LS | ||
| Don Muhlbach | |||
| Matt Camilli (UD) | |||
(PS) Practice Squad.
(UD) Undrafted Rookie Free Agent.
(TO) Try out.
